MSR微型记录仪在高海拔睡眠干扰检测中的应用

High Altitude Sleep Disturbances Monitored by Actigraphy and  Polysomnography

Yvonne  Nussbaumer-Ochsner,¹  Nicole Schuepfer,^1,2  Christoph Siebenmann,²
Marco Maggiorini,³  and  Konrad E. Bloch¹

Abstract

Nussbaumer-Ochsner,  Nicole Schuepfer, ChristophSiebenmann, Marco Maggiorini, and Konrad E.  Bloch.High altitude sleep disturbances monitored by actigraphy and  polysomnography. High.  Alt.  Med.  Biol.  12:229–236.—  Aims: Data  on sleep at altitude are scant due to the limited availability of  polysomnography. Therefore, we investigated whether actigraphy might serve as a  simple tool for monitoring sleep during altitude field studies. Methods: Fourteen  mountaineers participating in studies on dexamethasone prophylaxis of high  altitude pulmonary edema were monitored by actigraphy and polysomnography during  1 night at Zurich (490 m) and 4 nights at the Regina Margherita hut (4559 m).  Total sleep time (TST) estimated by actigraphy was compared to polysomnography  and subjective sleep quality. Results: In  64 comparisons, mean differences – 2SD  (bias – limits  of agreement) between actigraphy and polysomnography were 5 – 35  min for TST and 1 – 7%  for sleep efficiency. Correlations between subjective and polysomnographic  estimates of sleep efficiency and sleep latency were nonsignificant. Medians of  nocturnal oxygen saturation were 96% at 490 m and 74%–81% during nights 1 to 4  at 4459m (p < 0.05  vs. 490 m). Medians of polysomnographic TST were similar at 490 m (451 min) and  4559 m (377– 456 min during nights 1 to 4, p = NS)  but the proportions of slow wave and REM sleep were reduced and arousals were  more common (p < 0.05  all instances). Conclusion: Actigraphy  accurately estimates sleep efficiency and duration. Due to its portability and  simple use and the potential application over several weeks, it is a convenient  tool for investigating altitude effects on sleep during field studies.  

Key  words: Actigraphy, sleep disorders, hypobaric hypoxia. MSR145